Bard College offers free course in the humanities - Silobreaker

Published 16 hours ago by Daily Freeman

WHAT: The Bard College Clemente Course in the Humanities

WHEN: Tues. and Thurs. from 6 to 8 p.m. from Sept. to May

WHERE: The Kingston Library, 55 Franklin St., Kingston

DETAILS: Bard College will offer free college courses in the humanities in Kingston this fall. The classes, which offer college-level...

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Source: http://www.silobreaker.com/bard-college-offers-free-course-in-the-humanities-5_2265834641527144450

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Kristal Maner-Smith: Mass Spectrometry: The Real Process Behind Your Favorite Crime Drama's 'Lab Results'

Crime dramas have become a mainstay on network television programming. Each week viewers tune in to find out whodunnit and with which object: the rope, the candlestick, or the lead pipe? As portrayed in crime dramas, items recovered from a crime scene are sent to "The Lab," where a series of curious individuals -- magicians, perhaps -- analyze the samples and spit out an answer. This post aims to elucidate the mechanisms that analytical chemists employ to provide answers to the dastardly quandaries that cause Detective Stabler's pretty little brow to furrow.

The Big Black Box

By and large, mass spectrometers are among the most widely used instruments in analytical laboratories. These instruments are used to unequivocally provide the molecular weight of substances based on the mass-to-charge ratio of the substance in question. The molecular weight can then be used for identification if the substance is unknown. Many types of mass spectrometers exist; for the purpose of this post, the mechanics of a standard triple quadrupole mass spectrometer will be outlined.

As the name denotes, a triple quadrupole mass spectrometer consists of three quads: two mass filters, Q1 and Q3, separated by an RF-only collision cell, Q2. Each quad consists of four cylindrical rods that serve as electrodes. Rods opposite each other are held together electrically, one pair to the positive terminal of a DC power source and the other to the negative terminal. Radio frequency potentials are also applied to each pair of rods. Together, the voltages applied to the quad serve to propel charged particles (i.e., the ionized sample) along the length of the instrument.

Triple quadrupole mass spectrometers can be operated in two modes. In the first and most basic mode, MS mode, the molecular weight of the intact sample is determined. In MS/MS mode, the ionized sample is fragmented, or broken apart, in Q2 by collision with gas particles, and the molecular weights of the fragments are determined. The resulting fragments create a fingerprint, of sorts, that can also aid in identification of the sample. This feature proves particularly useful in distinguishing between substances that may have the same molecular weight, referred to as "isobaric species." To clarify, obtaining the molecular weight in MS mode is analogous to stepping on your bathroom scale to determine your body weight. However, there are undoubtedly many people with the same weight. This is where MS/MS comes in. Let us imagine that you were, say, broken apart into several unique pieces. Those pieces could be used to identify you out of the masses. (Suddenly, the whole sum-of-my-parts argument just got a lot more complex.)

The Front of the House

If the business end of the mass spectrometer can be described as an overworked, crowded kitchen, using the same restaurant analogy, the inlet can be thought of as the front door. It's what gets the sample into the instrument. Many types of inlets exist, and selecting the appropriate one is largely dependent upon the physical properties of the sample. If the sample is volatile and readily enters gas phase, gas chromatography (GC), though an analytical technique in its own right, can be used as a sample inlet. This is called GC-MS and is commonly used to analyze illicit drugs. Alternatively, if the sample is liquid and has UV absorbance, such as a blood sample, liquid chromatography (LC) may be used as the sample inlet.

Similarly, the ion source can be thought of as the reception area. To use more scientific terminology, the source is the part of the instrument that ionizes the sample and accelerates the newly charged particles into the instrument using kinetic energy. Remember, according to Newtonian physics, kinetic energy is dependent upon the mass of the substance as well as its speed; this property is utilized once inside the mass filter.

The Next Step

Now that we understand what a mass spectrometer is and how it operates, let's discuss how it can be used to answer a forensic question that might appear on a crime drama:

The blood sample of a victim, found unconscious near a popular nightspot, was sent to toxicology for analysis. LC-MS was performed on the plasma, and the resulting chromatogram and mass spectrum confirmed the presence of ketamine at a concentration of 20.0 mg/L . The plasma concentrations of norketamine were more than double than that of ketamine. GC-MS/MS analysis showed a racemic mixture of R and S enantiomers of the drug; a database search linked the ratio between the two isomers to a European supplier.

This information is invaluable to detectives attempting to solve a crime. Ketamine, though popular amongst partygoers for recreational drug use, is also commonly used as a date-rape drug. Traditionally, the drug has been used as an anesthetic between the range of 1.0 and 6.3 mg/L. The victim's plasma ketamine concentration is well outside that range, and from this it can be deduced that the cause of death was acute intoxication. Norketamine, a metabolic derivative of ketamine, is found at high concentrations when the drug is administered orally as opposed to intravenously. Using this fact, the detective can begin scouring the streets for dealers with merchandise in the tablet form over the more commercially available liquid version. Because the database match confirmed that the drug is likely European in origin, the detective can then begin narrowing down which crime syndicate might be involved.

?

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Source: http://www.huffingtonpost.com/kristal-manersmith/mass-spectrometry_b_1663689.html

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Amazon Due for Numerous Species Extinctions

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Source: http://news.yahoo.com/amazon-due-numerous-species-extinctions-181120760.html

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The ghosts that haunt China's economic landscape

Daniel Berehulak / Getty Images file

Chinese newlyweds pose for wedding photographs near to the Thames Town Church in Thames Town on November 19, 2010 in Songjiang, China.

By Ian Williams, NBC News

SHANGHAI, China -- It can take two or three hours to drive from bustling Shanghai to the sleepy streets of Thames Town, a new housing development built in the style of an English village complete with quaint pubs, red telephone boxes and statues of Harry Potter and James Bond. There's even an Anglican Church, though not a functioning one.

All that's missing are the people.

Thames Town was completed in 2006, cost a billion dollars to build, and was designed as home for 10,000 people. But shops and restaurants are boarded up, their doors chained.


Thames Town is one of the more bizarre examples of the madness of a construction frenzy and real estate bubble that has left the country with an estimated sixty four million empty homes. It was fuelled by easy money and rapidly rising prices.

Some economists see it as the biggest property bubble of all time - entire ghost cities built on speculation.

China reports slowest growth rate in 3 years

"Empty roads, empty buildings, empty neighborhoods, empty cities - all over China," says Gillem Tulloch,?Managing Director of Forensic Asia, who has traced the spread of the ghosts using Google Earth.

When I last visited his Hong Kong office, we sat in front of a big computer screen on which he zoomed in on city after city, row upon row of empty apartment blocks, lining deserted roads. All have what look like government buildings, museums and universities - the amenities of modern cities, but few cars or people to be seen.

By China's own estimate, there are twenty new cities being built each year. One recent housing development was designed to look like a village in Austria.

And it isn't just homes that lie empty: In the southern city of Dongguan, the New South China Mall, once touted as the world's largest, has been ninety nine per cent empty since it opened in in 2005 ? although gondolas are still at hand to offer visitors a cruise down its Venetian-style canals.

More recently, property prices have started to fall after the government took belated measures to end speculation. In some places, construction has slowed or ground to a halt. Construction equipment companies are struggling and there are reports of construction workers being laid off.

The problem for the Chinese government is that construction is a major component of GDP. Wasteful and mad though it may seem to outsiders, it has helped pump up growth figures, particularly after the 2008 financial crises, when the Chinese government injected into the economy a stimulus worth nearly US$700m. Much of that money went straight to those ghost towns.

Local government has come to rely on rising land prices for its funding, and local authorities have run up huge property-related debts. Nobody quite knows how exposed China's banks might be.

This is the background against which today's GDP figures should be seen. A lot of economists think the figures are pretty dodgy, and don't properly reflect the reality on the ground, but it?s still a significant slowdown by Chinese standards. And it poses a big dilemma for the government.

More savvy ministers know that property represents a dangerous bubble, and wants prices to fall further. They also know that the Chinese economy needs changing - re-balancing in economist-speak - away from wasteful construction projects and exports and today's domestic demand. That will also do a big favor to the world economy.

But with growth dipping below the psychologically important eight per cent level, and the communist party credibility on the line, there'll be a real temptation to open the financial taps again to boost the growth figures. The main?impact of that will be to keep Gillen Tulloch busy as he looks at yet more ghost towns, delaying the day of reckoning for China?s economy.

More world news from msnbc.com and NBC News:

Follow World News on msnbc.com on Twitter and Facebook

?

Source: http://behindthewall.msnbc.msn.com/_news/2012/07/13/12725483-the-ghosts-that-haunt-chinas-economic-landscape?chromedomain=worldnews&lite

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US retail sales of video games fell for 7th month

(AP) ? A new report says U.S. retail sales of video-game hardware, software and accessories fell for a seventh consecutive month.

Sales declined 29 percent in June to $700 million.

Sales of console and portable software ? the video games themselves ? fell 29 percent from a year earlier to $329 million. Sales of hardware fell 45 percent to $201 million. That was offset partly by a 4 percent increase in sales of accessories, to $170 million.

Thursday's report by NPD Group tracks sales of new physical products ? about 50 percent to 60 percent of the total spending. Excluded are sales of used games and rentals as well as digital and social-network spending.

The top-selling game was "Lego Batman 2: DC Super Heroes," from Time Warner Inc.'s Warner Bros. Interactive.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/495d344a0d10421e9baa8ee77029cfbd/Article_2012-07-12-US-TEC-Video-Game-Sales/id-88d2e4a5c0a64cf9b5df4ad15d34b252

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Dwarkadelhi Blog ? Tips About Filing For Private Bankruptcy

Previous Post: iPad Cases: Choose the one which suits your iPad the most and protects it against most of the outer risks &nbsp Next Post: Technology Is Playing Games with Vaporizers

When you are facing repossession in the Inside Profits Services, you could possibly feel as if you need to panic. Don?t stress because you will not be homeless or penniless, even though you file for individual a bankruptcy proceeding. See the suggestions in the following paragraphs, if you would like to understand more about the best way to file claims.

Incorporate all fiscal information and facts when filing for bankruptcy. Items that might not appear to be significant to you might be very important. Consist of all possessions like: vehicles, every cent of income, retirement life profile, stocks and shares and everything else which has importance. Furthermore, consist of any legal cases which are pending against you or another functions.

To be able to file for bankruptcy, you?ll will need professional authorized help. The earlier along the way you locate legal counsel, the higher. Usually do not worry about the cost of an a bankruptcy proceeding lawyer or attorney. Most attorneys who concentrate on this industry comprehend, your financial hardships. The earlier you start out taking advantage of their expert consultancy, the better away you will end up.

Before you decide to take into account filing for bankruptcy, you ought to create a pre-dedication if bankruptcy might be the proper selection. Initial, compose a list of cash flow, such as, income, child support, alimony, hire and then any other places you might have. Then, make a list of the monthly bills. These would come with mortgage, lease, auto payments, regular monthly charge card payments, food and gas. If your monthly bill full is a lot more in comparison to the earnings you attract, it could be a chance to seek the advice of a bankruptcy lawyer or attorney, who will help you have the ultimate decision.

Individual bankruptcy is a thing that is placed to assist you to. Do not feel that your daily life has finished because of a bankruptcy proceeding. You will find some limitations to issues that you can do, even so, these are only momentary. In addition there are businesses on the market that will help you obtain your life in purchase following individual bankruptcy. When you sent in or are thinking of processing, you should explore these businesses. There is certainly hope.

The very best policy for handling a bankruptcy proceeding is to avoid it to begin with. Almost certainly the easiest way to prevent monetary problems is always to plan ahead and also have enough savings to fall again on. Most monetary specialists suggest their clientele to maintain a savings account of a minimum of 3 months cash flow.

Be sure that you fully understand the effects of proclaiming yourself bankrupt. Upon having filed for individual bankruptcy, you are going to find it difficult to secure any credit history at all. While you might not see that impact like a big dilemma at the moment, if you would like invest in a residence later on, or hire a vehicle, maybe you are gonna want the credit score.

As stated initially from the post, personal a bankruptcy proceeding is always a choice for those who could not pay back their financial debt. Usually do not assume that you are left homeless or without having assets, in the event you file claims. More and more people are facing this alternative, no matter their earnings.

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Source: http://blog.dwarkadelhi.com/?p=34793

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Former Stanford, HP official to oversee UAW healthcare trust

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Source: http://news.yahoo.com/former-stanford-hp-official-oversee-uaw-healthcare-trust-231501151.html

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